![]() The quantum effect on ultrafast flow would provide new perspectives for nanochannel-based sensing systems for various key biomarkers, which may also promote the development of seawater desalination, energy conversion, and information systems. A possible explanation for the ultrafast flow of liquids and gases through nanopores based on wave-particle duality was also provided. While this alone makes them morally gray (or darker) characters, they also have a strangely close relationship. Chinese-born and raised by Gauron, one of the main antagonists of the series, both sisters are assassins who have no problem with killing. Meanwhile, the cutting-edge concept of nanochannels with quantum confined superfluid (QSF) is also discussed. The Second Raid features twin sisters, Xia Yu Fan and Xia Yu Lan. In the last episode, Yu Fan reveals that the Xia siblings were at odds with Amalgam, mostly for wiping out their town in China during the Second Chinese Civil War. In this Perspective, we mainly focus on exhibiting the great breakthroughs of solid-state nanochannels with distinct partitions of the inner wall (IW) and outer surface (OS). Recently, research has turned its attention to nanochannels with FE OS, which extends the range of measurable biomarkers to cells (50 μm) and promotes precise measurements. ![]() Therefore, the direct detection of targets with sizes larger than the diameters of nanochannels, i.e., cells, was hard to realize. ![]() However, traditional solid-state nanochannel-based sensing systems have mainly focused on the functional element modified on their inner-walls (FE IW), ignoring the ion-gating effect of functional elements modified on the outer surface (FE OS). In the past several decades, series of solid-state nanochannel-based sensing systems mainly focused on modifying functional elements on nanochannels have allowed for a highly sensitive and specific detection of various key biomarkers between 0.1 and 100 nm, including small molecules, nucleic acids, and proteins. Solid-state nanochannel-based sensing systems with various structures and morphologies have realized precise measurements for various key biomarkers due to their tunable physical structures and morphologies, controllable chemical properties, and a nanoconfined space-induced target enriching effect. ![]()
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